Spyre Therapeutics, Inc.

Public companies file this within four business days when something important happens that investors should know about before the next quarterly report.

Spyre Therapeutics, Inc. filed this to release information to investors under Regulation FD — usually a press release, conference presentation, or other event the company considers important. ) 221 Crescent Street Building 23 Suite 105 Waltham , MA 02453 (Address of Principal Executive Offices) (Zip Code) Registrant’s Telephone Number, Including Area Code: 617 651-5940 Not Applicable (Former Name or Former Address, if Changed Since Last Report) _______________________________________________________ Check the appropriate box below if the Form 8-K…